Extress List of Ingredients.

Extress is a Scientific Formulation of Natural Ingredients Including:
St. John's Wort (Hypericum Perforatum): Helps the body relax because of documented (1) MAO inhibiting properties, as well as (2) acts as a Serotonin re-uptake inhibitor, increasing the amounts of circulating Serotonin, and (3) also inhibits interleukin-6 (IL-6) and Cortisol, which cause anxiety and depression.

Taraxacum Officinale: Specifically useful for calming and generally for reducing excessive restlessness and tenseness.

Fructus Sophorae: Helps in reducing the feelings of being overwhelmed by external stimulation/ provocation.

GABA: Helps naturally relax all muscle tissue, relieving tension build-up and reducing blood pressure.

Chinese Herbs (Radix Condonopsis Pilosulae, Radix Heraclei, Radix Rehmanniae): Support the body in naturally combatting excessive tiredness, dissipating stress, releasing emotional tension. Traditionally useful as well for soothing over-activity in children.

Lavandula: Helps the body to naturally soothe and calm the nerves, dissipating stress and feelings of anxiousness.

5-HTP: The natural precursor to Serotonin and Melatonin, providing neurochemical balance during stress.

B Vitamins: Critically needed synergistic coenzymes needed by the body to enable relaxation both mentally and physically.

Specific Branched Chained Amino Acids (BCAAs) which aid in the preservation of muscle and neural tissue during times of stress and anxiety.

Supporting Amino Acids: Provides critical anti-stress buffering precursors for Brain, Central Nervous System (CNS) and Skeletal needs.

Specifically Targeted Micro-Nutritionals & More: Provides electromagnetic instructions to further support both mental and physical stress reduction of muscles, neural pathways and brain chemistry.

All Natural, Completely Safe, Effective and Guaranteed!

Buy Extress Natural Stress Relief Supplement - NDC# 67514-0094-3 1 Bottle - $26.95ea. Buy It Now 2 Bottles - $25.45ea. Buy It Now 3 Bottles - $23.95ea. Buy It Now 60 capsules per bottle. When feeling stress or tension, take 3 to 4 capsules every 3 hours, or as directed by a physician.

The Complete List of ingredients for Extress:

GABA - GABA (g-aminobutyric acid), one of the major inhibitory Amino Acid neurotransmitters of the central nervous system, is known to be an active a1- & a2-adrenergic antagonist, helping the body to relax the smooth muscle of arteries and veins. It acts via the GABA-A and GABA-B cell receptors to prevent neuronal depolarization and firing of an action potential occurring in muscles, stopping the muscle from contracting. An action potential is a rapid, transient, self-propagating electrical excitation of the membrane of electrically excitable cells, also known as a spike or nerve impulse (in neurons). Action potentials occur in nerve, muscle, and neuroendocrine cells and are generated and propagated through the actions of voltage-gated ion channels.An action potential is essentially a brief (approx. 1 ms long), regenerative change in the membrane potential which occurs in electrically excitable cells such as the smooth muscle in veins and arteries. Action potentials are essentially digital signals which encode information as a temporal sequence. With GABA, G-protein coupled receptor sites (the largest superfamily of cell-surface receptors) are competed for in smooth muscle, ensuring that smooth muscle of arteries and veins relaxes, and that action potentials do not fire. As the smooth muscle relaxes, arteries and veins begin to vasodilate, increasing their circumference, allowing more blood to flow which subsequently reduces blood pressure throughout the circulatory system.GABA, a quasi-amino acid, is thought to be one of the most powerful inhibitory neurotransmitters in the central nervous system operating as a chemical messenger to its neighbors. GABA is important in helping the body to naturally regulate nerve function and enhance the ability of vitamin B3 (niacin) to act. This is an amino acid which can be derived from yet another amino acid, glutamic acid. GABA, one of the so called three musketeers (GABA, Glutamine [GAM] and Glutamic acid [GA]), is believed to be capable of providing needed nutrition and energy for the brain.GABA has generally been found to be deficient in clinical and experimental seizure disorders and is the most widely distributed inhibitory neurotransmitter in the brain. GABA is helpful in bringing calmness to the body, promoting tranquility and peace in times of stress and anxiety. It is also a known precursor to another important neurotransmitter, gamma-hydroxybutyrate (GHB), which is a natural sleep inducing compound in the brain, encouraging the body to produce its own native tryptophan, which in turn is the natural precursor to the sleep neurotransmitter, serotonin.

L-Asparagine - Asparagine in its natural "L-" form, or L-Asparagine, Mol. Wt. 132, is an amino acid which is generally synthesized from aspartic acid and ATP, involved with energy cycles in the body, linking the Urea and the Krebs cycle together, and can provide the brain with energy as well.

Calcium Carbonate - Used as a Homeopathic or used simply as a micro-nutritional (mineral). (Homeopathic potencies accredit their strength and efficacy to the electromagnetic signatures of the original substrate; these are scientifically created dilutions and succussions of medicines such that generally not even a molecule of the original substrate or medicine is present in the medicine). As a Homeopathic or used simply as a micro-nutritional, it has demonstrated effectiveness against the following symptomology: colds, flu, full pulse with fever, excessive cold, nocturnal sweat, chiefly on the chest, inflammation of nose, swelling, ulcerated and scabby nostrils, aching eyes, burning eyes, sore throat, constricted, accumulation of mucus in the mouth, pains in the abdomen, tension and swelling, inflation, constipation, too frequent emission of urine, obstructed breathing, wheezing respiration, palpitation of the heart with anxieties and trembling movements, contractions in the region of the heart, cramping in the upper and lower limbs, muscle spasms and unrest.

Taraxacum Officinale - Historically used in Europe and China for feverish symptoms. The first known mention of the Dandelion, (from the French 'dent de lion': 'lion's tooth'), is as 'Taxacon' in Arabic texts of the 10th and 11th century. Fresh dandelion juice was once in great demand for its diuretic, antirheumatic, aperient qualities. The roots were often ground and used as coffee. This common herb has always been thought to be an unsightly weed for most weekend gardeners, but it holds much more majesty than most know. It is high in Vitamin A and C, Niacin (B3) and various minerals. Latex found in the leaves is an excellent naturally rich emollient used for facial steams, a cleansing milk and moisturizer.The roots are thought to increase the natural defensive fluids of the body and Dandelion flower, too, is a powerful cleanser of the system, purifying and eradicating harmful materials that become accumulated due to incessant poor health and illness. Dandelion has been a useful agent known to help the body relieve its stores of water (diuretic) as well as being felicitous for relieving stress and calming the nerves. In fact, it has been shown that in the spring harvest, the plant is known to contain mannite or mannitol, a substance known to be specifically useful for calming the nervous and generally reducing excessive restlessness and tenseness.

L-Isoleucine - This is an essential amino acid, one of the three critically important amino acids known as the Branched Chain Amino Acids (BCAA). BCAA's make up about 50% of the indispensable amino acids in the daily food supply. BCAA's are rather unique in that skeletal muscles may directly use them as an energy source. This is an anabolic substance which promotes protein synthesis. BCAA's are used up more rapidly in stressful conditions than other amino acids.Isoleucine is generally found to be deficient in chronically sick individuals. It is nutritionally useful in the formation of hemoglobin and is particularly important too in building the body's tolerance for stress. In fact, in experimental situations, deficiency of isoleucine resulted in the occurrence of marked tremors and the twitching of the muscles of the extremities in controlled studies.

L-Leucine - Leucine, or L-leucine in its natural form, is an essential amino acid. It is one of the three amino acids which are called the branched chain amino acids (BCAAs). BCAAs make up about 50% of the indispensable amino acids in the daily food supply. BCAAs are rather unique in that skeletal muscles may directly use them as an energy source. BCAAs are used up more rapidly in stressful conditions than other amino acids.Furthermore, research has suggested that the supplementation of BCAAs, especially leucine, can nutritionally aid the body in enlivening the liver, especially after extended periods of alcohol abuse or other drug related damage. Leucine is an anabolic substance which promotes the body's building-up of materials, accelerating protein synthesis. Leucine is a major nutritional metabolic regulator and is the only amino acid that can substitute for glucose in the fasting animal. It is an alternative energy source for the body, and the most able to help the body maintain blood sugar levels. Leucine is also thought to be a nutritional precursor to the naturally occurring, hurt-relieving chemicals in our body called leucine-enkephalins.

L-Valine - Valine in its "L-" form, L-Valine, is an essential amino acid. It is one of the three amino acids which are called the branched chain amino acids (BCAA). BCAA's make up about 50% of the indispensable amino acids in the daily food supply.BCAA's are rather unique in that skeletal muscles may directly use them as an energy source as they are an anabolic substance which promotes protein synthesis. BCAA's are used up in stressful conditions more rapidly than other amino acids.In controlled research experiments at the Brain-Bio Center in Princeton, New Jersey and elsewhere, removal of valine from the diet was thought to result in some noticeable but reversible changes to the red nuclei of the brain and the chief protein synthesizing machinery of the cells of the body. Deficiency of this and other amino acids causes the malabsorption of dietary nitrogen and protein. Valine is believed vital for mental function, muscle coordination and neural functioning.

DL-Phenylalanine - Phenylalanine, or L-Phenylalanine in its natural form, is an essential amino acid of tremendous nutritional importance, although often found low in the blood serum levels of vegetarians. It is a known nutritional precursor or forerunner of the neurotransmitters dopamine, norepinephrine (noradrenaline) and epinephrine (adrenaline) which latter substances control or affect heart rate and output, blood pressure, oxygen consumption, blood sugar levels, fat metabolism and other brain functions.Interestingly, "Phenylpropanolamine" (a substance which attempts to mirror some of the activities of phenylalanine) is a synthetic substance used to promote the release of CCK (cholescystokinin) in the stomach, a "satiation" hormone which naturally induces satiety, transmitting its chemical message to the brain, signaling the body that it should stop eating. Phenylalanine is reported to have similar attributes that may nutritionally decrease one's appetite naturally, having the same causes of the synthetic substance above.DL-Phenylalanine is also involved in the release of PEA, phenylethylamine, a neurotransmitter closely related to norepinephrine, and which can sensitize endorphin receptors to endorphins, and aids in the relief of depression and the regulation of mood. PEA, by itself, can increase the manufacturing of norepinephrine in the brain, a natural pick-me-up. Research has shown that most deprressed individuals have low levels of PEA, and that most antidepressant drugs raise PEA levels.The "D-" form of phenylalanine nutritionally inhibits the production of enzymes which defeat the naturally occurring "opiates" of the body, the endorphins and enkephalins, those naturally occurring "pain-relievers" that the body produces when faced with neurochemical messages of discomfort.More specifically, supplementation of the "D-" form of phenylalanine appears to lengthen the biochemical life of these naturally occurring substances by inhibiting enkephalinase, and endorphinases, the enzymes that breaks down our naturally occurring pain relievers, allowing the body to naturally "remove" itself from pain for longer periods of time. Interestingly, the body's natural pain relievers, the endorphins and enkephalins, are known to be some 400 times more powerful than morphine in their concentrated strength.The combined D- and L- forms of phenylalanine, known as DL-Phenylalanine, are used supplementally to simply complement the body's natural ability to relieve discomfort, while also ensuring that enough of the "L-" form has been supplied. Both D- and L- forms are naturally occurring in nature.

Choline Bitartrate - A trimethyl amino ethanol, Mol.Wt. 121, which occurs in biological tissues in the free form and as a component of certain phospholipids such as lecithins, plasmogens and sphingomyelins, important in the genesis and regeneration of neurological tissues. It displays a synergistic entity with the B vitamins in fat metabolism, cellular communication and is an essential precursor and component to acetylcholine, the major memory molecule of the brain, and key activator of nervous tissue throughout the central nervous system. Choline also acts as important source of labile methyl groups (-CH3). Although it can be synthesized by the body, it is yet certain whether the body can make all that it needs. It is generally found in most foods including egg yolks, whole grains, beef liver, legumes.

Fructus Sophorae - This particular herb has been used traditionally for stress and nervous agitation as well as possessing balancing qualities. Its calming influence is thought to balance energy pathways within the body and curb possible erratic messaging between body centers as well as increasing the threshold for sensation and reactivity, thus diminishing the confusion and demands of overwhelming external provocation.

Radix Condonopsis Pilosulae - This is a Chinese herb that has been nutritionally used to combat excessive tiredness, to strengthen the Chi (the "life energy" of the body) and to increase the integrity of the body's defense system so as to aid against the damaging conditions of stress.

Radix Heraclei - This select Chinese herb has been used for centuries to reduce unwanted internal pressure, relieve stress and provide for balance while comforting the system. Often used by herbalists to release tension which is often inappropriately trapped and subsequently creating body and emotional rigidness. Useful as well for the soothing of over-activity in children.

Radix Rehmanniae - This Chinese herb is known by herbal traditionalists to be used at times of stress and anxiety. It is thought to fortify the liver, enhance the function of the body's purifying system while also enhancing the blood and increasing circulation.

L-Glycine - This is an amino acid known to be the simplest molecular amino known, essential for the natural production of bile acids and nucleic acids. This is an important amino acid which is part of the tripeptide glutathione, a detoxifying agent essential for good health. Glycine is known to be a hypolipidemic agent (it acts to reduce lipid synthesis) and aids in the further reduction of cholesterol and triglycerides in the blood plasma.L-Glycine also acts like taurine in its natural calming properties. It is a major inhibitory neurotransmitter of the brain, readily and easily passing the brain-blood barrier, working in conjunction with GABA and Taurine as a natural anticonvulsant. Interestingly, depressed and epileptic patients often have low glycine levels in their plasma.Glycine is essentially important, too, in the photochemical reaction of the eye and is necessary for good vision. It is an important nutrient in wound healing, giving the skin its natural elasticity and bounce, protecting us from premature sagging and wilt, being a necessary constituent of collagen. In fact, glycine in the form of gelatin, a protein which is made up of 33% glycine, has been found to be useful in wound healing.

L-Threonine - Threonine is an essential amino acid, found naturally as L-Threonine, required for normal digestive and intestinal tract function. As a transfer agent and neurotransmitter, it is thought useful in helping the body to prevent an accumulation of fat in the liver. Severe deficiencies of threonine cause neurologic dysfunction of the musculature and lameness, as documented in scientific experiments.Threonine is a naturally occurring "immunostimulant" which nutritionally promotes the growth of the thymus (in general the stronger the thymus, the better one's health), while also complementing the body's promotion of cell immune defense function. Threonine, in this capacity, works naturally in conjunction with Lysine. Threonine has been identified as part of a naturally occurring antiinflammatory complex which may be related to the problems associated with joint discomfort, although this remains unproven.Perhaps of importance as well is the fact that this amino acid has been reportedly successful in the nutritional care of some genetic spasticity disorders, but more research is needed before any true relationships can be defined. Threonine levels have also been noted to be low in chronically depressed persons at Princeton's Brain-Bio Institute, and subsequent supplementation was found for some of these to lead to the control of their depression.

Hypericum Perforatum - The Greek name Hypericum means "over and apparition" in the belief that the herb was so obnoxious to evil spirits that only a small scent would cause them to fly away. Scientifically, this herb has been found to inhibit the growth of Mycobacterium tuberculosis in vitro (but remains unproven in human populations). However, within human populations, it has been shown to have effective antibacterial and antiviral properties and wound healing abilities because of the naturally occurring alkaloid, Hypericin and Hyperforin. There are also a number of other components now thought to be useful in this regard including Flavonols, Xanthones and Phloroglucinol derivatives. These compounds are especially effective because they can cross the blood-brain barrier (important for HIV infection). Recent research (Lancet, Volume 350, November 1997) has shown that St. John's Wort also contains substantial amounts of Melatonin, both in the leaves and flowers. Since Melatonin and Serotonin activity are directly related (Melatonin can be derived from Serotonin), this gives more biochemical evidence and understanding of its antidepressant activity, helping to increase levels of Serotonin.Taken internally, it is useful in reducing the symptoms of psychological disturbances, depressive moods, anxiety, bipolar dysfunction, stress, sadness and nervous unrest. St. John's Wort, in particular, has demonstrated clear antidepressant effects in a number of double blind studies, and is recognized in Germany (Commission E) as an herbal antidepressant often prescribed by German physicians (66 million daily prescriptions in 1994 alone). In a meta-analysis conducted by Klaus Linde, et al., Ludwig-Maximilians-Universitat, Munich, Germany, published in the August 1996 issue of the British Medical Journal, St. John's Wort was "significantly superior" to placebo for mild to moderate depression. It should be noted that in these studies the extract of St. John's Wort was used (as does V„xa formulas) and not the non-standardized herb itself. The study consisted of 23 randomized clinical trials involving 1,757 patients examined in single and combination preparations with either placebo or standard antidepressive treatment. Antidepressant activity (MAO inhibition which retards one of the enzymes responsible for monoamine breakdown and thus acts to increase the amount of Serotonin and Norepinephrine in the central nervous system) is thought to be due to the Dianthrone derivative including Hypericin, Pseudohypericin, Frangula-emodin Anthranol (and a mixture of the precursors, proto-hypericin and hypericodehydrodianthrone). It has been found in German studies that Hypericin irreversibly inhibits type A and B MAO in human populations. In other clinical trials, the use of St. John's Wort has led to significant excretion of 3-methoxy-4-hydroxyphenlyglucol, a marker for the beginning of an antidepressant reaction in women. Although originally thought to be only an MAO inhibitor alone, similar to drugs Nardil and Parnate, it now appears that St. John's Wort, like Prozac, acts as a Serotonin re-uptake inhibitor, increasing the amounts of circulating Serotonin to brain cells. In addition, St. John's Wort has an inhibiting effect on another chemical called interleukin-6 (IL-6), which raises levels of Cortisol, a hormone that is elevated in depression. By indirectly reducing Cortisol levels, St. John's Wort produces further antidepressant effects. The added advantages of using St. John's Wort in the recommended dosages is that there are no side effects, as there are with synthetic antidepressants. The only possible side effect is possible photosensitization (although it's thought at least 4 grams consumed daily must be used for this to occur), especially in fair skinned people, which can generally be prevented with adequate supplementation of vitamin B2 and L-Taurine.The use of St. John's Wort has demonstrated an improvement in the symptoms of anxiety, dysphoric mood, loss of interest, hypersomnia, anorexia, depression, insomnia, obstipation, psychomotor retardation and feelings of worthlessness in women populations. In animal studies too, hypericin from St. John's Wort appears to reduce aggressive behavior while increasing the amount of exploratory behavior in foreign environments. This herb has historically been used as a pain-reducing agent for joint pain, headaches and nervous conditions. It has also been used for the diuretic activity on smooth musculature. This is an herb which can also be used in one's garden salad as well as being a useful and advantageous agent in the soothing of bruises, wounds, stressed veins, minor irruptions of the skin and sunburn when applied topically, as well as being useful cosmetically as a skin tightener. External applications have used the oily Hypericum preparations for treatment and post-therapy of acute and contused injuries, myalgia and first-degree burns.Also used as an effective Homeopathic medicine (botanical) (Homeopathic potencies accredit their strength and efficacy to the electromagnetic signatures of the original substrate; these are scientifically created dilutions and succussions of medicines such that generally not even a molecule of the original substrate or medicine is present in the medicine). As a Homeopathic or used simply as a micro-nutritional, it has demonstrated effectiveness against the following symptomology: "It is called the 'Arnica of the nerves'. In injuries to nerves and parts rich in nerves...or in open wounds that are exceedingly painful, it is eminently suited. Great nervous depression and loss of blood from lacerated wounds. Nails or splinters in feet, slivers under nails, mashings of fingers by hammer or crushing of toes by letting things fall on them, are conditions benefited by Hypericum. It modifies or arrests sloughing and is...valuable as a soother of pain after surgical operations... very useful in injuries to the coccyx...ascending neuritis after a fracture, or any form of traumatic neuritis." (Dewey) -convulsions after every slight hurt or concussion; -wounds from crushing, as mashed fingers, especially tips; -extreme sensitiveness of punctured wounds; -open painful wounds with general prostration from loss of blood and great nervous depression; -spinal concussions; cervical vertebrae very sensitive to touch; -violent pains and inability to walk or to stoop after a fall upon coccyx (Lilienthal).

Lavandula - Tranquility and purity are inherent in the unique fragrance of lavender. But it has many other properties less known but perhaps more beneficial. Historically, this herb has been found to soothe and calm the nerves, relieving stress and feelings of anxiousness when taken internally.When applied topically, it has been useful in relieving skin sores and inflammation and is quite soothing when applied to bath water, presumably because of the sweet inhalant combining with the warmth of the surrounding waters. There are even notions of it being useful in the soothing of irritable and unmindful children by placing the herb-oil in their bath water, or placing a small bunch beneath their pillow at night!

Valeriana Officinalis - The name of this herb is derived from the Latin valere, "to be in health," and is an ancient "medicinal herb" which was of certain popularity. It was found in the medicine bags of Canadian Indians, the Iroquois, and was purportedly used as a wound cleanser. This herb was used among the Nordic, the Persians and the Chinese as well. The only thing "bad" about the plant is its odor, which brings to mind the smell of stale perspiration, although cats are apparently quite attracted to it, and the perfume industry uses its strange muskiness in some of its concoctions. Funny enough, its old name V. phu is the likely origin of our colloquial expression for an "undesirable scent."Valerian returned to some prominence and popularity medicinally during the first World War, being used to treat shell shock and nervous stress in army hospitals. It is still effective when taken internally, the root acting to soothe a person's stress, relieving sleeplessness, calming the body and emotional distress, and tiredness and exhaustion. Most recently it has demonstrated sedative, sleep promoting actions, being useful for general nervousness and restlessness, insomnia and sleeping disorders based on nervous conditions. Active substances are thought to be essential oils and mono and sesquiterpenes.

5-HTP - 5-HTP is the direct precursor to Serotonin, and a safe alternative to L-Tryptophan (Ironically, L-Tryptophan has been cleared of any role in the EMS outbreak, it being a problem of contamination and not with the amino acid itself, and is still used in infant formulas and parenteral IV solutions). 5-HTP is normally converted in the body from L-Tryptophan. Thus, 5-HTP is thought to be able to more directly influence Serotonin production within the Hypothalamus than L-Tryptophan did. 5-HTP is some 10 times more effective than ordinary L-Tryptophan. As Serotonin levels increase, so too can Melatonin levels which can aid in normalizing sleep patterns (just 2 steps further removed form Serotonin).

L-Histidine - Histidine, or L-Histidine as it is found in its natural form, is an essential amino acid for children, and conditionally so for adults. It is thought to be effective in increasing and improving female libido (female sexual arousal) and is believed necessary for orgasm in women (as per preliminary research findings), yet paradoxically, depresses sexual stimulation in males.It is the precursor of the ubiquitous neurohormone and neurotransmitter histamine which is involved in smooth muscle function and the dilation or expansion of blood vessels; Histamine (not Histidine) is also stored in mast cells, which upon Immune System alert, are ruptured, emptying their contents into the blood stream. Histidine is also involved in the maintenance of myelin sheaths which insulate the nerves, much like a rubber coated extension cord keeps you from being electrically shocked.Histidine is required for normal auditory function and stimulates the production of red and white blood cells. It is also helpful in moderation to nutritionally aid in the removal of toxic metals from the body, and is thought particularly beneficial as a nutrient for arthritics, having a mild soothing effect because of a histidine-copper-threonine complex that exists naturally in the blood. Quite interestingly, Arthritic individuals generally have abnormally low blood histamine and low serum histidine, as well as low levels of histamine within their synovial fluid - the transparent, viscid, lubricating fluid secreted by joint membranes.

L-Taurine - Taurine, commonly found in its "L-" form, L-Taurine, is an amino acid which serves as an inhibitatory neurotransmitter in the brain, acting much like the amino acid GABA. Because of these properties, it is thought to naturally possess properties which would reduce nerve instability and misfiring.Taurine is generally found in areas of the body which normally experience high electrochemical activity, such as the eye, brain and heart. Its most important function is to stabilize nerve cell membranes which are constantly receiving and transmitting neuro-signals. In part, taurine's nutritional properties prevent neurons from becoming unstable and misfiring erratically or too rapidly, which is generally what happens in situations of seizure and in some cases of epilepsy.As a nutrient, it has also been found useful in soothing the uncontrolled agitation and reactive misfiring of neurons, resembling seizures or seizure-like activities, although their significance for severe neurological dysfunction is unknown. It is thought to nutritionally aid in the health and motility of sperm as well, as has been shown experimentally.

Calcium Pantothenate-B5

Magnesium - A mineral that comes in many forms and abilities to assimilate. The presence of magnesium nutritionally helps metabolize calcium, Vitamin C and carbohydrates; nutritionally promotes healthy teeth, nerves and muscles; and energizes and fights against sadness, stress and unhappiness. Magnesium is excellent in nutritively helping many skin troubles, being a necessary electrolyte essential for all cell functions, from neural pathways acting in neuromuscular transmission, to being an important cofactor in cell metabolism, required for lipid/fat metabolism, thiamine utilization and enzyme reactions.Magnesium works with many of the B vitamins and is a necessary part of amino acid synthesis and general functioning as well. Perhaps its most important function is its involvement in Phosphate-transfer reaction and changes in energy states within the body.

Pyridoxine HCL-B6

OptiZinc - An antioxidant made by the InterHealth Co. in California, the same company that makes ChromeMate & ActiVin. OptiZinc has demonstrated synergistic effects with other antioxidants, far surpassing the abilities of common vitamin antioxidants such as vitamin A, E, and C. The antioxidant power of OptiZinc has been confirmed in multiple university-based studies. It also helps glutathione reserves in the body, as well as possibly reduce homocysteine levels because of its molecular configuration.

Niacinamide-B3

Gotu Kola - This herb dates back to India where it enjoyed a reputation of being a plant which promoted longevity, and has some historical significance too, in that it has been used by religious organizations which claim that it heightens spiritual powers. More practically, their leaves are known to have a marked nutritionally energizing effect on the brain without increasing stress. Often confused with the kola nut, it is not related; nor does Gotu Kola contain any caffeine.In fact, its properties are said to allow a brightness of the spirit while bestowing a calming influence at the same time. It contains a natural soothing agent believed to stimulate the energy levels within the body without raising stress levels. This legendary herb is also considered a "tonic," a natural water eliminator, stimulating the body to release stored water masses. Several studies have shown that Centella aids in the development of strong connective tissue, actually stimulating the production of compounds which make up the "ground substance" where collagen fibers are embedded. Centella has also demonstrated some enhancement of the venous flow into the lower limbs, aiding in some improvement of varicose veins. The extract's effect on cellulite appears to be linked to this latter capacity for its ability to promote connective tissue structure and reduce sclerosis of target areas (hardening).

Cobalamin-B12

Folic Acid - This is a vitamin necessary to promote normal red blood cell formation. It is thought to be an important catalyst aiding in the maintenance of the nervous system, the health of the intestinal tract and genitals and related organs, white blood cells, and normal patterns of growth. In 1981, it was conclusively demonstrated that folic acid supplementation could prevent more than half of the cases of spina-bifida and other neural tube defects. The FDA has finally announced that folic acid is essential to the diet and especially necessary within the diets of pregnant women, now recommending 400 mcg per day to reduce the risk of neural tube deficits and birth disorders. Recently, research has demonstrated that elevated levels of folic acid (800 mcg: twice that of the USRDI's) helps prevent heart attacks by reducing homocysteine levels. However, in yet other studies, lower levels of folic acid (200 mcg - 400mcg daily) along with other B vitamins appear to decrease levels of homocysteine production, and lower levels of these amount do not interfere with homocysteine's natural degradation as some have postulated, since if homocysteine is not immediately converted to methionine or thereafter removed properly from the system, heart attacks become significantly more likely. In any case, low dose Folic Acid (200 mcg - 400 mcg) intake appears to be just as effective than higher dosages (800 mcg). When used with vitamin B-5 and PABA, vitamin B-9 may help in the delay of hair graying and promote healthy skin (unproven). The rather obtuse idea that Vitamin B9 could mask a vitamin B12 deficiency is now considered a misnomer, as the criticism was originally based on a reference to a study in 1947 before B12 was properly isolated. Folic Acid is not only safe, it is essential for healthy life. Results of a recent meta-analysis in Oxford, England at the Radcliffe Infirmary demonstrated that Vitamin B12 and Folic Acid (and to lesser extend by Vitamin B6, whose presence is necessary to convert homocysteine to the amino acid L-cysteine) were necessary vitamins involved in the body's cleansing process called methylation, wherein dangerous homocysteine levels are reduced. Lowering homocysteine levels has been shown to reduce the risk of cardiovascular disease, for as much as 30%-40%. Folic acid can be increased to .5 mg up to 5 mg with adequate amounts of B12 (1mg.) for these purposes. (BMJ, 316(7135):894-898, March1998)

Aconitum napellus - Used as a Homeopathic or used simply as a micro-nutritional (botanical). (Homeopathic potencies accredit their strength and efficacy to the electromagnetic signatures of the original substrate; these are scientifically created dilutions and succussions of medicines such that generally not even a molecule of the original substrate or medicine is present in the medicine). As a Homeopathic or used simply as a micro-nutritional, it has demonstrated effectiveness against the following symptomology: great agitation and tossing of the body with anguish, inconsolable irritability, cries, tears, groans, complaints and reproaches; -vexed at trifles; takes every joke in bad part; -great, inconsolable anxiety; -dislike to talk, answers laconically; -ailments from fear, fright, vexation (Clarke) -sleeplessness after midnight, with anxiety, restlessness and tossing about from arterial excitement; -sleeplessness from a nervous fear that he was not going to sleep, or from local irritation especially in the intestinal tract; -sleeplessness, eyes closed, caused by fear, fright, anxiety; anxious, vivid dreams; -sleeplessness of infants and of the aged (Lilienthal).Also effective as a Homeopathic medicine when befit with flu-like symptoms such as: "Acute sudden and violent invasion (of disease) with fever call for it...Sudden and great sinking of strength...First remedy in inflammations and inflammatory fevers...Burning in internal parts; tingling, coldness and numbness...Cold stage (of fevers) most marked; cold sweat and icy coldness of face; gooseflesh; coldness and heat alternate; evening chilliness soon after going to bed; cold waves pass through him; dry heat, red face; mental anguish, restlessness, etc.; sweat drenching parts lain on." (Boericke)

Argentum nitricum - Used as a Homeopathic or used simply as a micro-nutritional (mineral preparation). (Homeopathic potencies accredit their strength and efficacy to the electromagnetic signatures of the original substrate; these are scientifically created dilutions and succussions of medicines such that generally not even a molecule of the original substrate or medicine is present in the medicine). As a Homeopathic or used simply as a micro-nutritional, it has demonstrated effectiveness against the following symptomology: very impulsive; always in a hurry but accomplishes nothing; -hurries restlessly to fulfil engagements, fears to be late when there is plenty of time; -times seems to pass very slowly; -easily angered or excited, anger brings on symptoms; -nightly nervousness with heat and fullness in the head; -"building castles in the air by day: monstrous visions by night" (Clarke);-tormented by strange ideas or emotions; -nervous, impulsive and hurried, yet timid and anxious, fearsome; -dreads ordeals; -incoherence; faltering speech, gait, etc. (Boger) -thinks his understanding will and must fail; -faintish and tremulous; fearful and nervous; melancholic; -impulsive, wants to do things in a hurry; peculiar mental impulses; -memory weak; errors of perception; time passes too slowly (Boericke).

Coffea crudum - Used as a Homeopathic or used simply as a micro-nutritional (botanical). (Homeopathic potencies accredit their strength and efficacy to the electromagnetic signatures of the original substrate; these are scientifically created dilutions and succussions of medicines such that generally not even a molecule of the original substrate or medicine is present in the medicine). As a Homeopathic or used simply as a micro-nutritional, it has demonstrated effectiveness against the following symptomology: mental and physical excitability; -vivacity and excessive loquacity; vivacity and elevation of the imagination with acuteness of the intellectual faculties; -anxiety of heart and of conscience, with apprehensions; -sleeplessness from over-excitability of mind and body; -great anguish, cannot be composed, is not able to hold the pen, trembles; -excessive weeping and lamentations over trifles; -effects of sudden emotions, fear, fright, over-fatigue, long journeys (Clarke)It has also demonstrated effectiveness against the following symptomology: sleeplessness from overexcitement of mind and body, all senses are more acute; -sleeplessness from joy or agreeable surprise; from long night-watching; from excessive use of coffee; -persistent insomnia of children without (discoverable) cause (Lilienthal) -"Indicated when the patient cannot get to sleep for simple cerebral activity, thoughts crowding in upon him and clinging to him in spite of all his efforts at detachment." (Hughes)

Epiphegus virginica - Used as a Homeopathic or used simply as a micro-nutritional (botanical). (Homeopathic potencies accredit their strength and efficacy to the electromagnetic signatures of the original substrate; these are scientifically created dilutions and succussions of medicines such that generally not even a molecule of the original substrate or medicine is present in the medicine). As a Homeopathic or used simply as a micro-nutritional, it has demonstrated effectiveness against the following symptomology: ill effects of physical or nervous overstrain; -any unusual exertion or excitement aggravates (such as going on a visit, or doing a day's shopping, etc.) (Clarke) -a remedy for sick, neurasthenic and nervous headaches brought on or made worse by exertion; -headaches from nerve tire caused by mental or physical exhaustion; -sick headache coming on whenever deviating from ordinary pursuits (Boericke).

Kali phosphoricum - Used as a Homeopathic or used simply as a micro-nutritional (tissue salt). (Homeopathic potencies accredit their strength and efficacy to the electromagnetic signatures of the original substrate; these are scientifically created dilutions and succussions of medicines such that generally not even a molecule of the original substrate or medicine is present in the medicine). As a Homeopathic or used simply as a micro-nutritional, it has demonstrated effectiveness against the following symptomology: "Corresponds to nervous dreads, over-sensitiveness to noise, restless and suspicious, ill effects of fright, grief, fear, sleeplessness, excessive and exhausting mental labor. It is one of the best remedies we have (for neurasthenia) and is probably often indicated. All observers agree that it is the most useful of the various phosphates." (Dewey)It has also demonstrated effectiveness against the following symptomology: corresponds to states of adynamia and decay; conditions arising from want of nerve power; -"remember it in treatment of suspected malignant tumors"; (Boericke) -clinical conditions: anemia; atrophy; brain, softening of; carbuncle; dysentery; gangrene; paralysis; pneumonia; puerperal fevers; ulcers (of skin); whitlow; septic states and septic fevers, noma, scurvy, typhoid and typhus fevers (Clarke) -"Kali phosphoricum is indicated when there is enzyme damage in the cells...especially indicated in reversible enzyme blockages such as may occur after retoxic treatment of influenza or infectious diseases...presenting symptoms of autonomic dystonia with nervousness, depressive moods, weakness of memory, anxiety, sleeplessness and in serious cases of melancholia with a hysterical and hypochondriacal element...chronic inflammations are also typical of the indications...sequelae of serious septic illnesses especially after retoxic (ie, allopathic) treatment.." (Reckeweg)It has demonstrated effectiveness against the following symptomology: despondency, anxiety, fearfulness, tearfulness, home-sickness, agoraphobia, weak memory; -sensory nerves: pains with sensation of paralysis; -motor nerves: weakness of muscles and nerves even to paralysis; -trophic fibres of the sympathetic nervous system: retarded nutrition, even total arrest in a limited area of cells and then softening (of tissue); -morose, irritable, averse to be talked to, everything is too much; lethargy; extreme lassitude and depression, apprehensive; loss of memory, cannot recall names or words, mind sluggish but will act if aroused; exhaustion after moderate mental effort; restless, nervous, starting; perverted affections; indifferent and captious; -twitching of muscles of arms and fingers; numbness of right arm and hand, no feeling in finger-tips; -legs numb; fidgety feet; -"Depression is the characteristic of its action, conversely it cures depressed states of mind and body, hypochondriasis, hysteria, neurasthenia, nervous insomnia, spasms of irritable weakness, paralysis" (Clarke)Also, as a Homeopathic or used simply as a micro-nutritional, it has demonstrated effectiveness against the following depressive symptomology: "This remedy is indicated in derangements of the nervous system such as neurasthenia, prostration, insomnia, loss of mental vigor...patient is gloomy, depressed, with a loss of memory and tending to look on the dark side of things...of service in melancholia and mania that arise as a result of overstrain of the mind or from an exhausting drainage that affects the nerve centers; also homesickness, when haunted by visions of the past." (Blackwood); Especially useful in certain Homeopathic potencies for mental exertion: -indisposition to meet people; -anxiety, nervous dread, lethargy; -extreme lassitude and depression; very nervous; -loss of memory; brain-fag; -cerebral anemia; headache of students and those worn out by fatigue; -slightest labor seems a heavy task; -worse excitement, worry, mental and physical exertion (Boericke).

Nux vomica - This is a Homeopathic medicine derived from Bachelor's Buttons (botanical). (Homeopathic potencies accredit their strength and efficacy to the electromagnetic signatures of the original substrate; these are scientifically created dilutions and succussions of medicines such that generally not even a molecule of the original substrate or medicine is present in the medicine). As a Homeopathic or used simply as a micro-nutritional, it has demonstrated effectiveness against the following symptomology: tingling and itching in ears; -insupportable itching in nose; obstruction of nose; dry coryza and stoppage of nose; -sensation of contraction of gullet with danger of suffocation; -difficult respiration, shortness of breath, asthmatic constriction and oppression of chest, worse after dinner; hay asthma (Clarke)This Homeopathic medicine has also demonstrated effectiveness against the following symptomology: "Useful in irritable, excited, oversensitive patients with defective memories, loss of energy, patients with whom 'everything goes wrong', trifling ailments are unbearable; there is intellectual incapacity and insomnia, nightmares, and if all these conditions are associated with dyspeptic troubles the remedy is all the better indicated." (Dewey) -"Especially indicated in the irritable, bilious, quarrelsome, malicious individual who is disposed to anger, spite and deception; also in persons who are suffering from the bad effects of coffee, tobacco, alcoholic stimulants, overeating, over-mental exertion, sedentary habits, loss of sleep, abuse of drugs..." (Blackwood) -"In leaving off tobacco should be taken every four hours..." (Clarke, "The Prescriber") -very irritable, sensitive to all impressions; ugly, malicious; sullen, faultfinding; insomnia; -abuse of tobacco (Boericke).Especially useful in certain Homeopathic potencies concerning problems of hypertension and blood circulation: -"Stands midway between acute and chronic congestion of the brain...it is especially in hyperemia of some standing that it proves valuable, when occurring in strong frames and in persons of sedentary occupations, given to mental exertions and in the habit of taking plenty of animal food (meat) and alcohol." (Hughes).